by Dr. Ed Weber | Oct 2, 2019 | PCa Commentary
The suggestion that a few (usually 3 – 5, i.e., ‘oligometastatic’) lesions at the time of biochemical failure after primary treatment might represent an indolent disease state with limited potential for additional spread. This hypothesis was first made in 1995... by Dr. Ed Weber | Oct 2, 2019 | PCa Commentary
* The first study of active surveillance (AS) was started in 1996 at the University of Toronto byDr. Lawrence Klotz. It was first reported in the literature in 2002. In the ensuing 20 years AS has become increasingly accepted as a management approach to biopsy... by Dr. Ed Weber | Sep 5, 2019 | PCa Commentary
Radium-223 combined with Lupron demonstrated a median 3.6 month extension of overall survival, compared to the placebo (14.9 v 11.3 months). This was the outcome of a 928 man randomized trial (ASYMPCA) in asymptomatic or mildly symptomatic men with... by Dr. Ed Weber | Aug 29, 2019 | PCa Commentary
The Natural History of Prostate Cancer and the Prognostic Utility of PSA Doubling Time. We are indebted to UroToday for making available online the informative presentation at ASCO 2019 by Dr. Catherine Marshall: “Outcomes of Men with Recurrent MO [metastasis... by Dr. Ed Weber | Jul 16, 2019 | PCa Commentary
Managing PSA Recurrence Following Primary Radiation Therapy: Evolving Regimens for Focal Treatment Biochemical recurrence following primary irradiation is relatively common. “A recent series of 2694 patients treated with doses above 78 Gy revealed 10-year... by Dr. Ed Weber | May 10, 2019 | PCa Commentary
Radioligand therapy (RLT) – i.e. PSMA directed endoradiation with Lutetium-177 – has been developed to the extent that it is a realistic option for men with late stage, heavily pretreated metastatic castration-resistant prostate cancer. The national...