Top Ten Steps to Fight Prostate Cancer
If you have been diagnosed with prostate cancer, these steps will help you understand what to do next.
Better Way to Screen for Drug-resistant Prostate Cancer?
Researchers at the University of Toronto may have found a better way to identify prostate cancer patients who may not respond to first-line treatments. Tumors that are drug-resistant, have circulating tumor cells that often times have high levels of particular...
Another Tool in the Treatment of Recurrent Prostate Cancer
A recent article published in the New England Journal of Medicine reports a study showing the benefit of a new hormonal medication in reducing the development of prostate cancer metastases. About 1200 men from 26 countries throughout the world were enrolled in the...
Qualifying for Social Security Disability With Prostate Cancer
The information below was provided by Disability Benefits Help. We hope our viewers in the United States will find it helpful. Men who have been diagnosed with prostate cancer might qualify for Social Security disability benefits. The Social Security Administration...
New Study finds Single High Dose Rate Brachytherapy is Effective against Prostate Cancer
New research shows that a single high-dose brachytherapy treatment is as effective and safe against localized prostate cancer as many low dose over time. The researchers at Oakland University’s William Beaumont School of Medicine in Royal Oaks, Michigan, said “It is...
PCa Commentary #121: AR-V7: The Clinical Utility of Knowing Your Status … And When Is the Information Most Useful.
A test for the splice-variant AR-V7, Oncotype Dx AR-V7 Nucleus Detect (Genomic Health, Inc.), has become commercially available. This Commentary will focus on the clinical significance of test results — their predictive and prognostic value. The Major Foundation...
When it comes to your health, you are your best advocate.
The PSA blood test…sounds harmless enough, and not that hard to do; and yet, according to a 2016 study published in JAMA International Medicine found that PSA (prostate specific antigen) testing- a blood test used to screen for prostate cancer- is on the decline. The...
Can Exercise Improve Prostate Cancer Patients’ Survival?-Global Study to find out
The study is called the Global Action Plan 4 Global Prostate Cancer (GAP4), and will include more than 150 researchers from around the world. The clinical trial will be looking to see if exercise can improve cancer symptoms and delay the disease’s progression. The...
Big Dangers when it comes to Pain management
When it comes to “pain management”, most people automatically think of over the counter medications. They take the prescribed dose, the medication goes to work, and the pain is managed; often times it is short-lived, and they can move on from it. But, for many...
Actor Stephen Fry reveals he has prostate cancer
Last week, Actor Stephen Fry revealed that for the past few months, he has been battling prostate cancer. Fry credits early detection: "I felt my life was saved by early intervention so I would urge any of you men of a certain age to get your PSA levels checked." ...
Don’t Allow Prostate Cancer to Drive You and Your Partner Apart
Facing a cancer diagnosis can be tough to handle as a couple. It’s safe to assume that a prostate cancer diagnosis will be stressful for any relationship. The possible unwanted changes that can occur before, during, or after treatment can be very trying, and couples...
Recurrence Anxiety Strikes Unexpectedly
The fear of recurrence weighs heavily on the minds of every cancer survivor, some more than others. For some it can be an overwhelming fear experienced on a daily basis, and for others, less frequent. For many patients, recurrence anxiety strikes most often around...
Prostate Cancer claims more lives than breast cancer in the UK
According to recent numbers released this past week, there are now more prostate cancer related deaths in the UK than breast cancer deaths. You can read the original article here: “Prostate cancer now kills more in UK than breast cancer.” It is amazing to see the...
Dealing With Depression When You Have Cancer
Addressing depression in cancer patients is a vital part of the care provided by healthcare providers. In some cases, healthcare providers should be doing a better job in asking patients going through cancer treatment about their emotional health, and to encourage...
Tips for meeting with your doctor
Before you meet with your doctor for the first time, it’s a good idea to formulate a list of questions you want answered. Be sure to write them down, so you don’t forget to ask any of them. Also, bring someone along for moral support. Having them there will help...
FAQ’s to Help Overcome Your Fears of a Prostate Biopsy
Your Urologist felt a “suspicious lump” and wants to schedule you for a prostate biopsy. Two emotions come to the forefront….anxiety and fear. The source of these emotions are from the unknown- not knowing what expect during the procedure and not wanting to know the...
How to Avoid Buyer’s Remorse After Your Prostatectomy
A study published in the journal Research and Reports in Urology found that the rate of prostatectomy-related regret increases over time, with up to 47 percent of men reporting regret five years after surgery. You can read the original article here: "How to Avoid...
Researchers in Spain may have identified a potential therapeutic target for advanced Prostate Cancer.
Through studying the 3D structure of the androgen receptor, Researchers in Spain have identified a key protein responsible for its activation. Identifying this protein, called TFIIF, makes it a possible therapeutic target for advanced prostate cancer. You can read...
7 Things to do when facing the seemingly never-ending Misery of Cancer
For many Cancer Patients, they face a serious problem, when their cancer-related symptoms are always front-and-center in their life. Pain control or quality-of-life issues can make life miserable every minute of every day. You can read the original article here: “7...
The Key Molecular Process that Leads to Prostate Cancer Metastasis has been uncovered by Researchers
In a new Swedish study, researchers at Umeå University have identified a key protein called Snail1, which appears to be crucial to the spread of prostate cancer cells. You can read the original article here: “Researchers Uncover Key Molecular Process that Leads to...
A new Phase 1 Trial shows ProscaVax Vaccine stopped Prostate Cancer Progression in 80% of participants.
OncBioMune Pharmaceuticals’ new prostate cancer vaccine, ProscaVax, stopped cancer progression in 80% of patients in their Phase 1 clinical trial after 6 injections. You can read the entire article here: “ProscaVax Vaccine Stopped Prostate Cancer Progression in 80% of...
PCa Commentary
Expert Commentary On The Latest Prostate Cancer Topics
Written by Dr. Ed Weber
PCa Commentary is a well-researched, clearly presented commentary targeted to medical providers and others interested in current prostate cancer treatment. Each PCa Commentary edition offers an analysis of new developments in the field of prostate cancer with essays discussing and evaluating treatment management options for this disease.
RADIOLIGAND THERAPY (RLT) with 177-LUTETIUM: Forthcoming Treatment Option Likely to Upgrade the Management of Advanced Prostate Cancer in the Near Future.
This Commentary is prompted by two items relevant to this rapidly advancing field: “The Prostate,” April 2018, published: “Meeting report from the Prostate Cancer Foundation PSMA-directed radionuclide scientific working group,” by multiple authors actively involved in...
PCa Commentary #122: New Guidance on the Management of PSA Rise in the Setting of Nonmetastatic Castration-Resistant Prostate Cancer (nmCRPC): A New Role for Apalutamide and Enzalutamide
At the 2018 Genitourinary Session of the American Association of Clinical Oncology two presentations reported similar findings which offer management guidance for men whose PSAs are rising despite androgen suppression but have no objective evidence of metastatic...
PCa Commentary #121: AR-V7: The Clinical Utility of Knowing Your Status … And When Is the Information Most Useful.
A test for the splice-variant AR-V7, Oncotype Dx AR-V7 Nucleus Detect (Genomic Health, Inc.), has become commercially available. This Commentary will focus on the clinical significance of test results — their predictive and prognostic value. The Major Foundation...
PCa Commentary #120: METASTASIS DIRECTED THERAPY: What Can Be Learned From The First Reported Prospective, Randomized, Multicenter Phase II Clinical Trial?
In December 2017 the JCO published the trial results of Ost and colleagues: “Surveillance or Metastasis -Directed Therapy for Oligometastatic Prostate Cancer Recurrence”. Up to this time there have been numerous retrospective and observational studies of varying...
PCa Commentary #119: KNOW YOUR BRCA STATUS: The Clinical Importance of Mutations in Genes that Repair Injury to DNA
The message is clear. At diagnosis 6% of men carry mutations in the BRCA 1 or BRCA 2 gene. At the stage of metastatic castration-resistant prostate cancer nearly 12% of men exhibit these germline (inherited) mutations. Finally, as the course of the disease progresses...
PCa Commentary #118: Two Developments are New- and when integrated suggest a pathway forward in prostate cancer management.
The word is out that a survival benefit accrues when either abiraterone (Zytiga) plus prednisone (AA/P) or docetaxel (Taxotere) are added to standard androgen deprivation therapy (ADT) in the treatment of de novo metastatic hormone sensitive prostate cancer and also...
PCa Commentary #117: RADIOLIGAND THERAPY IS FOR REAL
RADIOLIGAND THERAPY IS FOR REAL — and as the technique is further developed it will assume an important role in the treatment of advanced prostate cancer. This article has benefited from review and comments by Dr. Scott Tarawa, Associate Professor Clinical Medicine,...
PCa Commentary #116: THE AXUMIN SCAN FOR PROSTATE CANCER — Increasing Availability Throughout the US and to be Available at Swedish Medical Center in October
The Axumin Scan (also termed: 18F-fluciclovine) — What is it? This PET/CT study was approved by the FDA in May 2016 for evaluation of men with rising PSA’s after primary treatment with surgery or radiation. It is a total body “functional” scan based on the cellular...
PCa Commentary #115: PARP INHIBITION – AN EMERGING NEW TREATMENT: A Primer on its Clinical Utility in Treating Metastatic Prostate Cancer with BRCA-like Mutations
I would like to thank Dr. Bruce Montgomery, University of Washington and Seattle Veterans’ System, and Dr. Song Zhao, Cancer Institute, Swedish Medical Center, Seattle, for their valuable input into this article and especially in the sections regarding their...
PCa Commentary #114: ACTIVE SURVEILLANCE: Who Are The Best Candidates and What Are the Best Outcomes?
Active surveillance (AS) is now considered the preferred management option for men with low-risk prostate cancer. The guidelines for all the major organizations relating to prostate cancer recommend a discussion of AS with patients diagnosed on biopsy with low-risk...
UNDERSTAND PROSTATE CANCER.
What is Prostate Cancer?
What is Prostate Cancer, the Symptoms, Risk Factors? What does the Prostate do, where is it located?
Diagnosed with Prostate Cancer?
What tests confirm the presence of prostate cancer? Learn how doctors diagnose prostate cancer.
Treating Prostate Cancer.
Patients have options when it comes to the prostate cancer treatments. Learn about your options.
Prostate Cancer Surgery or Radiation ???
Need Treatment? YOU NEED THIS STUDY! This fifteen year study follows 119,000+ patients treated for prostate cancer, to see who became Prostate Cancer Free. Treated once. No more treatment. No recurrence. Get your copy of the study to discuss with your family and Doctor.
Help other men make better treatment decisions.
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